旧版栏目

生物工程与技术中心

曲剑波(教授)

时间:2017-03-05浏览:6043

»姓名: 曲剑波

»职称: 教授/硕导


»系属: 生物与能源化工系

»最高学位: 博士

»学科: 化学工程与技术

»所学专业: 生物化工

»电子邮箱:jbqu@upc.edu.cn

»联系电话:0532-86981133

»地址邮编:山东省青岛市黄岛区长江西路66号中国石油大学(华东)化学工程学院,266580

»个人主页:

学习与工作经历

1992.9-1996.7   抚顺石油学院,石化系,化学工程专业,学士

1996.7-2002.5   中国石油兰州石化总公司,工程师

2002.9-2005.7   四川大学,化学工程学院,生物化工专业,硕士

2005.9-2009.6   中国科学院过程工程研究所,生化工程国家重点实验室,生物化工专业博士

2009.7-2012.11  中国石油大学(华东),化学工程学院,生物工程与技术中心,讲师

2012.12-2015.9  中国石油大学(华东),化学工程学院,生物工程与技术中心,副教授

2015.10-2016.10 澳大利亚新南威尔士大学,Center for Advanced Macromolecular DesignCAMD)访问学者

2016.11-2020.11 中国石油大学(华东),化学工程学院,生物工程与技术中心,副教授

2020.12-至今    中国石油大学(华东),化学工程学院,生物与能源化工系,教授

研究方向

1. 超大孔色谱分离介质的开发及应用研究

2. 功能性聚苯乙烯微球/纳米球的制备与应用

3. 血液净化材料的开发与应用研究

4. 靶向纳米给药系统的设计开发

5. 利用RAFT/ATRP方法设计、合成功能高分子

学术兼职

国家自然科学基金、北京市自然科学基金及浙江省自然科学基金项目函评专家;山东省自然科学基金结题评审专家;教育部学位与研究生教育发展中心评审专家;中国化工学会会员。

Sensors & Actuators B, Analytica Chimic Acta, Journal of Chromatography A, Colloid & surface B, Materials Today CommunicationsInternational Journal of Pharmaceuticals, Materials Science & Engineering C等国际SCI期刊审稿人。

主讲课程

本科:《化工原理》、《生物化工基础》、《健康生活中的化学奥秘》;研究生:《生物分离工程》、《生化反应工程及反应器》

指导研究生情况

独立指导硕士研究生16人,已毕业8人;协助指导硕士研究生13人,已毕业11人。

承担科研课题

近年来主持国家自然科学基金面上项目2项,山东省自然科学基金面上项目2项,山东省重点研发计划项目1项,重质油国家重点实验室自主研发课题1项,青岛开发区重点科技发展计划项目1项,学校自主创新项目2项。参与国家自然科学基金2项,国家科技重大专项子课题1项。

1.国家自然科学基金面上项目(21776310),主持,2018-2021

2.山东省自然科学基金面上项目(ZR2017MB019),主持,2017-2020

3.山东省重点研发计划项目(2019GGX102062),主持,2019-2021

4.国家自然科学基金面上项目(21176257),主持,2012-2015

5.山东省自然科学基金面上项目(ZR2010BM001),主持,2010-2013

获奖情况

1.提高稠油热采收率的新型蒸汽封窜协同化学降黏技术及工业化应用,2019,中国石油和化学工业联合会技术发明三等奖,1/6

2.大孔琼胶糖微球分离介质的开发与产业化,2013,青岛市黄岛区科技进步二等奖,2/6

期刊论文

[1] Wen-Shu Peng, Yang-Yang Lin, Yong-Jun Sun, Bing-Qing Zhu, Shi-Hai Li, Jing-Li, Jian-Bo Qu*. One-Pot Fabrication of Hierarchically Bicontinuous Polystyrene Monoliths with Homogeneous Skeletons and Glycopolymer Surfaces. Macromolecular Rapid Communications, 2021, 42, 2100154

[2] Jian-Bo Qu*, Yang-Yang Li, Yuan Liu, Bing-Qi Zhu, Yong-Jun Sun, Wen-Shu Peng, Jing Li. Synthesis of Bimodal Open-Porous Polystyrene Monoliths with Glycopolymer Surfaces for High-Speed Protein Chromatography. ACS Applied Polymer Materials, 2021, 3, 2657-2666.

[3] Jian-Bo Qu*, Yang-Yang Li, Qing Li, Wen-Shu Peng, Jiankun Huang, Jing Li, Benjamin Edem Meteku, Jingbin Zeng*. In-situ grafting temperature-responsive hydrogel as a bifunctional solid-phase microextraction coating for tunable extraction of biomacromolecules. J. Chromatogr. A, 2021, 1639, 461928.

[4] Meng-Qi ChenWen-Shu Peng, Yang-Yang Lin, Hong-Liang Gu, Yong-Jun Sun, Bing-Qi Zhu, Jing-Li, Jian-Guo Liu, Jian-Bo Qu*. Crown Ether-Assisted Synthesis of Polystyrene Nanoparticles: Implications for Biomedicine and Electronics. ACS Applied Nano Materials, 2020, 3(11), 10787-10795.

[5]曲剑波*,彭文舒,蔺洋洋,李丹丹,李静,刘建国*,张晓云. 利用原子转移自由基反应在超大孔聚苯乙烯微球表面接枝含糖聚合物刷. 高分子材料科学与工程, 2020, 36 (5), 12-19.

[6] Jian-Bo Qu*, Yuan Liu, Jun-Yi Liu, Guan-Sheng Huan, Sheng-Nan Wei, Shi-Hai Li, and Jian-Guo Liu*. One-Pot Synthesis of Bimodal Gigaporous Polystyrene Microspheres with Hydrophilic Surfaces. Macromolecules, 2018, 51, 4085-4093.

[7] Jian-Bo Qu*, Shi-Hai Li, Yu-Liang Xu, Yuan Liu, Jian-Guo Liu*. Inherently fluorescent polystyrene microspheres as a fluorescent probe for highly sensitive determination of chromium (VI) and mercury (II) ions. Sensors & Actuators B, 2018, 272, 127-134.

[8] Jian-Bo Qu*, Robert Chapman, Fan Chen, Hongxu Lu, Martina H. Stenzel*. Swollen micelles for the preparation of gated, squeezable, pH-responsive drug carriers. ACS Appl. Mater. Interfaces, 2017, 9 (16), 13865–13874.

[9]Jian-Bo Qu*, Yu-Liang Xu, Yu Liu, Yanan Wang, Yuanhong Sui, Jian-Guo Liu, Xiaojuan Wang*. Inherently fluorescent polystyrene microspheres for coating, sensing and cellular Imaging. Colloid. Surface. B, 2017, 152, 475-481.

[10] Jian-Bo Qu*, Yu-Liang Xu, Jun-Yi Liu, Jing-Bin Zeng, Yan-Li Chen, Wei-Qing Zhou, Jian-Guo Liu. Thermo- and pH-responsive polymer brushes-grafted gigaporous polystyrene microspheres as a high-speed protein chromatography matrix. J. Chromatogr. A, 2016, 1441, 61-67.

[11]Jian-Bo Qu*, Yu-Liang Xu, Jun-Yi Liu, Shi-Hai Li, Wei-Qing Zhou, Jian-Guo Liu*. Chemical coating polysaccharide on gigaporous polystyrene microspheres as a high-speed protein chromatography matrix. Polym. Eng. Sci., 2016, 56(12), 1407-1414.

[12] 徐玉良,曲剑波*,王晓娟,刘俊毅,李士海,刘建国*. 一种聚苯乙烯荧光微球的制备及发光机理研究. 高分子学报, 2016,10, 1368-1373.

[13] Jian-Bo Qu*, Yan-Li Chen, Guan-sheng Huan, Wei-Qing Zhou, Jian-Guo Liu, Hu Zhu, Xiao-Yun Zhang*. Preparation and characterization of a thermoresponsive gigaporous medium for high-speed protein chromatography. Anal. Chim. Acta, 2015, 853, 617-624.

[14] 曲剑波*,陈艳丽,宦关生,周炜清,张晓云*. 一种温敏型超大孔生物分离介质的制备及表征. 高分子学报, 2015, 1, 57-64

[15] Jian-Bo Qu*, Guan-Sheng Huan, Yan-Li Chen, Wei-Qing Zhou, Jian-Guo Liu, and Fang Huang*. Coating Gigaporous Polystyrene Microspheres with Cross-linked Poly(vinyl alcohol) Hydrogel as a Rapid Protein Chromatography Matrix. ACS Appl. Mater. Interfaces, 2014, 6(15), 12752−12760.

[16] 曲剑波*, 宦关生, 陈艳丽, 邵荟荟. 利用ATRP反应合成含糖聚合物影响因素的探讨. 高分子材料科学与工程, 2014, 30, 43-48.

[17] Jian-Bo Qu*Guansheng HuanYanli ChenHuihui ShaoLi Wang. Exploration of the bulk atom transfer radical polymerization of styrene. Advances in Polymer Technology, 2013, 32(4), 21371.

[18] Jian-Bo Qu*, Hui-Hui Shao, Guang-Lun Jing, Fang Huang. PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies. Colloids and Surfaces B: Biointerfaces, 2013, 102, 37-44.

[19] Jian-Bo Qu*, Hui-Hui Shao, Juan Li, Guang-Lun Jing, Jian-Guo Liu, Wei-Qing Zhou. Hydrophilization of gigaporous polystyrene microspheres with saccharide as high-speed protein chromatography base support. Reactive & Functional Polymers, 2012, 72, 606-612.

[20] Jian-Bo Qu*, Yong-Dong Huang, Guang-Lun Jing, Jian-Guo Liu, Wei-Qing Zhou, Hu Zhu, Jian-Ren Lv. A novel matrix derivatized from hydrophilic gigaporous polystyrene-based microspheres for high-speed immobilized-metal affinity chromatography. J. Chromatogr. B2011879, 1043-1048.

[21] Jian-Bo Qu, Xing-Zhong Wan, Yan-Qin Zhai, Wei-Qing Zhou, Zhi-Guo Su, Guang-Hui Ma*. A Novel Stationary Phase Derivatized from Hydrophilic Gigaporous Polystyrene-based Microspheres for High-speed Protein Chromatography. J. Chromatogr. A. 2009, 1216, 6511-6516.

[22] 曲剑波, 肖元丕, 王佳兴, 苏志国, 马光辉*. IE701离子交换树脂对胆红素吸附性能的研究.中国医药工业杂志, 2009, 40, 135-138.

[23] Jian-Bo Qu, Wei-Qing Zhou, Wei Wei, Zhi-guo Su, Guang-Hui Ma*. An Effective way to Hydrophilize Gigaporous Polystyrene Microspheres as Rapid Chromatographic Separation Media for Proteins. Langmuir, 2008, 24, 13646-13652.

[24] Jian-Bo Qu, Wei-Qing. Zhou, Wei Wei, Zhi-guo Su, Guang-Hui Ma*. Chemical Modification and Characterization of Gigaporous Polystyrene Microspheres as Rapid Separation of Proteins Base Supports. J. Polym. Sci. Part A: Polym Chem., 2008, 46, 5794-5804.

[25] Jian-Bo Qu, Ling-Yin Chu*, Mei Yang, Rui Xie, Lin Hu, and Wen –Mei Chen. A pH-Responsive Gating Membrane System with Pumping Effects for Improved Controlled Release. Advanced Functional Materials, 2006, 16, 1865-1872.

[26] 曲剑波, 杨眉, 褚良银*, 朱家骅, 陈文梅, 谢锐. 等离子体诱导接枝聚合法制备pH感应开关膜. 高分子材料科学与工程, 2005, 21(2), 93-97.

专利

[1]曲剑波, 靖广伦, 刘建国, 肖梓军, 朱虎(2014.一种制备高磁含量壳聚糖纳米球的方法, ZL 201210060861.X

[2]曲剑波, 王晓娟, 陈艳丽, 宦关生, 朱虎(2015. 一种聚苯乙烯材料表面亲水改性的方法, ZL 201310315379.0

[3]曲剑波, 陈艳丽, 宦关生, 张晓云, 黄方(2016.一种快流速温敏型超大孔生物分离介质的制备方法, ZL 201410142858.1

[4]曲剑波, 宦关生, 邵荟荟, 刘建国, 朱虎(2017. 一种亲水性超大孔聚合物微球及其制备方法, ZL 201310475774.5

[5]曲剑波, 刘源, 黄方, 李士海, 徐雅妍, 王晓娟, 刘建国(2018. 一种具有挤压和开关效应的纳米药物载体的制备方法.ZL201611218315.9

[6]曲剑波, 徐玉良, 王晓娟, 刘俊毅, 刘建国2018. 一种制备自发荧光聚苯乙烯材料的方法及产品, ZL 201510672974.9

[7]曲剑波, 刘源,李士海,蔺洋洋,彭文舒,张晓云,黄方(2021.一种双孔道亲水性双连续聚合物整体柱的制备方法, ZL 201811578771.3

书目章节

[1] 张晓云, 曲剑波编著. 《高分子化学实验(双语)》, 中国石化出版社, 202011月出版.

[2] Jian-Bo Qu, Fang Huang, Wei-Qing Zhou, Fei Gao, Guang-Hui Ma. “Gigaporous polystyrene microspheres and their applications in high-speed protein chromatography” In Polystyrene: Synthesis, Characteristics and Applications; Cole Lynwood Eds.; Nova Science Publishers: Hauppauge, 2014; Chapter 4; PP 75-114.