张志庆（教授）

  姓    名：

张志庆

  职    称：

　教授

  导师类别：

　博士生导师

  系    室：

化学系

  研究领域：

　胶体与界面化学

  电子邮箱：

   zhangzq@upc.edu.cn

  实 验 室：

　基础楼A713

◎教育背景

1996-2000， 山东大学化学学院，理学学士

2000-2005， 山东大学胶体与界面化学教育部重点实验室硕博连读，博士研究生

2011-2011， 北京外国语大学，教育部公派出国留学英语高级班

2012-2013， 美国加州大学，国家公派访问学者

2018-2018， 复旦大学，中国石油大学（华东）中层干部专题培训班

◎工作经历

2005-2007， 华东理工大学化学与分子工程学院，讲师，教研室副主任

2007至今， 中国石油大学（华东），教授，博士生导师，历任教研室主任，系副主任，副院长

2012-2012， 苏丹喀土穆炼厂研究生班讲学

◎研究方向

[1] 纳米分子工程：包括核酸的滚环合成，DNA生物大分子组装体的构筑，新型纳米传感器用于疾病和环境的靶向检测，基因编辑和基因治疗，药物靶向递送和癌症精准诊疗等。

[2] 胶体与界面化学：包括新型表面活性剂、两亲嵌段高分子、疏水缔合共聚物等精细化学品的合成、性质研究及应用。

[3] 油田化学品：包括原油破乳剂、降凝剂、降粘剂、污水处理剂、缓蚀阻垢剂、沥青分散剂、新型油气压裂液等。

◎科研项目

主持及参与科研项目20余项：

[1] 2024.01-2026.12，山东省自然科学基金面上项目，多价靶向   DNA@AuNPs 纳米载体用于乳腺癌的光热-药物联合治疗的研究；

[2] 2023.01-2025.12，山东省自然科学基金面上项目，基于DNA 折纸组装的纳米火车载药用于白血病的多价靶向治疗；

[3] 2020.05-2022.12，中石油重大科技项目，“石油＋”学科交叉专项课题，天然气水合物开采的压裂技术研究；

[4] 2019.07-2022.06，山东省自然科学基金面上项目，多价核酸适配体的滚环合成及其用于抗癌药物的靶向输送；

[5] 2017.08-2020.06，山东省自然科学基金，含多价适配体的长链DNA负载金纳米粒子靶向检测癌细胞的研究；

[6] 2017-2020，国家自然科学青年基金“基于缓蚀应用的氮杂环类表面活性剂分子构筑与吸附性能研究”   ；

[7] 2016-2019，山东省自然科学基金——联合专项，表面活性剂在酸性溶液中对碳钢的缓蚀性能与机理研究；

[8] 2015.05-2017.06年，校自主创新科研计划项目科技专项，Gemini型表面活性剂清洁压裂液用于页岩气的体积改造；

[9] 2014.12-2017.12年，教育部留学回国人员科研启动基金，含多价适配体的嵌段DNA大分子用于抗癌药物的靶向输送；

[10] 2014.09-2016.09年，青岛市科技计划项目，科技成果转化引导计划（应用基础研究），页岩气的清洁压裂开采研究；

[11]2013.6-2015.5，粘弹性表面活性剂清洁压裂液的微观结构及成胶/破胶机理的研究，自主创新科研计划项目；

[12] 2012-2013年，国家留学基金委留学基金，CSC201206455009；

[13] 2012.01-2014.12年，国家自然科学基金项目“聚合物负载离子液体的制备及其脱除燃料油中噻吩类硫化物的基础研究”；

[14] 2011.08-2014.06年，山东省自然科学基金青年基金项目“多肽基两亲嵌段聚醚的胶束自组装及用于医药纳米载体的研究”；

[15] 2010-2013年，中石化胜利油田高新技术产业化项目“抗高温粘弹性表面活性剂压裂液的研制” ；

◎代表性论文及专利

在国内外学术期刊上发表150余篇学术论文，其中被SCI/EI收录100余篇，他引4000余次。授权和申请发明专利15项，编写教材和专著3部。

1.论文

【2023至今】

[1]   Ruyan Zhang, Ting Zhou*, Xiaobing Huo, Huan Du, Gan Ning, Tianxin Weng,   Xiufeng Wang, Guodong Zhang, Fang Wang, Zhiqing Zhang*. Multivalent   aptamer-DNAzyme conjugates for cancer cell detection and gene-chemotherapy   synergistic tumor therapy, Langmuir, 2025, online.

[2]   Jinfeng Zheng, Xiufeng Wang, Huan Du, Ruyan Zhang, Xiaobing Huo, Ting Zhou,   Guodong Zhang, Fang Wang, Qianxiong Zhou,* Zhiqing Zhang*. Multifunctional   Ru(III)/Fe3O4/DNA nanoplatform for photothermal-enhanced photodynamic and   chemodynamic cancer therapy, Journal of Inorganic Biochemistry, 2025, 262:   112771.

[3]   Liqian Wang, Fang Wang*, Ruyan Zhang, Huan Du, Gan Ning, Xiufeng Wang, Ting   Zhou, Guodong Zhang, Zhiqing Zhang*. “Lily of the valley”-like   Au@RCA nanoplatformas polyvalent aptamers-targeted drug delivery system for   combined photothermal and chemo-tumor cell therapy, Colloids and Surfaces A:   Physicochemical and Engineering Aspects, 2025, 704: 135436.

[4]   Wenhui Ai, Ge Chen, Jiayao Chen, Yao Jin, Xiufeng Wang*, Ting Zhou, Zhiqing   Zhang, Fang Wang, Guodong Zhang. Cu-MoOx-based nanozyme with enhanced   peroxidase like activity for quinolone antibiotics detection, Spectrochimica   Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325: 125117.

[5]   Huan Du, Fang Wang*, Ruyan Zhang, Xiaoyan Yan, Jinfeng Zheng, Ting Zhou,   Xiufeng Wang, Guodong Zhang, Zhiqing Zhang*. Rolling circle   amplification-based self-assembly to form a GPS-Nanoconveyor for   in vitro targeted imaging and enhanced gene/chemo (CRISPR//DOX) synergistic   therapy, Biomacromolecules, 2024, 25 (8), 4991-5007.

[6]   Xiaobing Huo, Zhiqing Zhang*, Huan Du, Ruyan Zhang, Jinfeng Zheng, Ting Zhou,   Xiufeng Wang, Guodong Zhang, Fang Wang*. Dual-targeting nanoplatform based on   rolling circle amplification for enhanced multimodal synergistic treatment of   breast cancer, ACS Applied Polymer Materials, 2024, 6: 10936-10950.

[7]   Xiaoyan Ding, Guodong Zhang*, Xiqiu Wang, Kaitao Xin, Fang Wang, Ting Zhou,   Xiufeng Wang, Zhiqing Zhang*. Preparation of thickened P(AA-AMPS) copolymers   by inverse emulsion polymerization and evaluation of fracturing and oil   flooding performance, Journal of Molecular Liquids, 2024, 415: 126400.

[8]   Xiqiu Wang, Fang Wang*, Xiaoyan Ding, Kaitao Xin, Guodong Zhang, Ting Zhou,   Xiufeng Wang, Zhiqing Zhang*. Hydrophobically Associated Amphiphilic   Copolymer Fracturing Fluid with Dual Functions of Fracturing and Flooding for   Enhanced Oil Recovery, Journal of Molecular Liquids, 2024, 413: 125995.

[9]   Xiufeng Wang*, Yunyun Zhang, Wenhui Ai, Yao Jin, Ge Chen, Zhiqing Zhang*,   Guodong Zhang, Ting Zhou, Fang Wang. A ratiometric fluorescence sensor based   on Mn doped ZnS QDs for highly selective detection of ascorbic acid, Colloids   and Surfaces A: Physicochemical and

Engineering   Aspects, 2024, 701: 134868.

[10]   Xiqiu Wang, Fang Wang*, Yu Zhang, Xiaoyan Ding, Guodong Zhang, Ting Zhou,   Xiufeng Wang, Zhiqing Zhang*. Novel hydrophobic associative copolymers for   natural gas hydrate fracturing fluids. Journal of Molecular Liquids, 2024,   398: 124192.

[11]   Xiqiu Wang, Zhiqing Zhang, Yukun Zhang, Guodong Zhang, Fang Wang. Study on   Association Behavior and Solution Properties of Poly(Acrylic Acid-Alkyl   Polyoxyethylene Acrylate) Amphiphilic Copolymers, Iranian Polymer Journal[J].   2024, 33(7): 943-953.

[12]   Xiaoyan Yan, Fang Wang*, Huan Du, Xiaobing Huo, Ruyan Zhang, Ting Zhou,   Xiufeng Wang , Guodong Zhang, Zhiqing Zhang*. The switch of the DNA   tetrahedral tweezers controlled by mercury ions, Spectrochimica Acta Part A:   Molecular and Biomolecular Spectroscopy, 2024, 306: 123614.

[13]   Weizhen Sun, Luyao Zang, Xia Zhang, Chenqi Zhang, Zhiqing Zhang, Xiufeng   Wang, Guodong Zhang, Fang Wang and Ting Zhou*. Facile synthesis of C30-AuNPs   for the effective catalytic reduction of nitrophenols and azo dyes, New   Journal of Chemistry, 2024, 48, 4548

[14]   Xiufeng Wang*, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang*, Ting Zhou, Fang   Wang, Guodong Zhang. Dual-mode fluorescence and colorimetric sensing of   sulfide anion in natural water based on near-infrared Ag2S quantum dots and   MnO2 nanosheets complex, Spectrochimica Acta Part A: Molecular and   Biomolecular Spectroscopy, 2024, 307: 123626.

[15]   Yao Jin, Wenhui Ai, Ge Chen, Guodong Zhang, Fang Wang, Ting Zhou, Zhiqing   Zhang, Xiufeng Wang*. Dual-mode fluorescent and colorimetric sensing of   thiourea and aluminum ion in natural water based on CuO nanoparticles,   microchimica acta, 2024, 191: 666.

[16]   Xiqiu Wang, Shixiu Wang, Fang Wang*, Guodong Zhang, Xiufeng Wang, Ting Zhou,   Zhiqing Zhang*. New Anionic Gemini Surfactant Viscoelastic Fluid for Clean   Fracturing of Natural Gas Hydrate, Journal of Molecular Liquids, 2023, 390:   122913.

[17]   Zhiqing Zhang*, Dongyan Xu, Jiawei Wang, Ruyan Zhang, Huan Du, Ting Zhou,   Xiufeng Wang, Fang Wang*. Rolling circle amplification-based DNA   nano-assembly for targeted drug delivery and gene therapy, Biomacromolecules,   2023, 24(1): 439-448.

[18]   Siqi Wang; Yao Jin; Wenhui Ai; Xiufeng Wang*; Zhiqing Zhang; Ting Zhou;   Guodong Zhang;

Fang   Wang ; H2O2 actuated molybdenum oxide nanodots: multi-enzyme-like activities,   leverage of Fenton reaction, and dual-mode sensitive detection of alendronate   sodium, Nano Research,

2023,   16(10): 12106-12115.

[19]   Ruyan Zhang, Zhiqing Zhang*, Huan Du, Jiawei Wang, Xiufeng Wang, Ting Zhou,   Fang Wang*. A Nucleolin-Activated Polyvalent Aptamer Nanoprobe for Detection   of Cancer Cells, Analytical and Bioanalytical Chemistry, 2023, 415:   2217-2226.

[20]   Lixia Yang, Zhiqing Zhang*, Ruyan Zhang, Huan Du, Ting Zhou, Xiufeng Wang,   Fang Wang*. A “turn on” fluorescent sensor for Hg2+ detection based on   rolling circle amplification with DNA origami-assisted signal amplification   strategy, Journal of Photochemistry and Photobiology A: Chemistry, 2023, 438,   114515. 

[21]   Siqi Wang, Xiufeng Wang*, Bingyuan Du, Yao Jin, Wenhui Ai, Guodong Zhang,   Ting Zhou,

Fang   Wang, Zhiqing Zhang*. Hydrogen peroxide-assisted and histidine-stabilized   copper-containing nanozyme for efficient degradation of various organic dyes,   Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 287,   122084.

[22]   Wenjing Li, Ting Zhou *, Weizhen Sun, Mengting Liu, Xiufeng Wang, Fang Wang,   Guodong Zhang, Zhiqing Zhang*. A conjugated aptamer and   oligonucleotides-stabilized gold nanoclusters nanoplatform for targeted   fluorescent imaging and efficient drug delivery, Colloids and Surfaces A:   Physicochemical and Engineering Aspects, 2023,657, 130521.

[23]   Xiufeng Wang*, Yunyun Zhang, Yao Jin, Siqi Wang, Zhiqing Zhang*, Ting Zhou,   Guodong Zhang, Fang Wang. An Off-Off fluorescence sensor based on ZnS quantum   dots for detection of glutathione, Journal of Photochemistry and Photobiology   A: Chemistry, 2023, 435, 114264.

[24]   周亭，张霞，王虹，王一蕾，张志庆*。DNA-AuNCs 催化降解有机污染物综合性实验，实验技术与管理，2024，41(2): 114-121。

【2019-2022年】

[25] Jiawei Wang, Zhiqing Zhang*, Ruyan Zhang, Huan Du, Ting Zhou, Fang   Wang*. “Willow Branch” DNA self-assembly for cancer dual-target and   proliferation inhibition, Langmuir, 2022, 38 (38): 11778-11786.

[26] Zhiqing Zhang*, Nana Liu, Zichen Zhang, Dongyan Xu, Shuai Ma,   Xiufeng Wang, Ting Zhou, Guodong Zhang and Fang Wang*. Construction of   aptamer-based molecular beacons with varied blocked structures and targeted   detection of thrombin, Langmuir, 2021, 37(29): 8738-8745..

[27] Hong Wang, Ting Zhou*, Wenjing Li, Zhen Wang, Yanbing Liu, Fang   Wang, Xiufeng Wang, Guodong Zhang, Zhiqing Zhang*. Oligonucleotides-templated   gold nanoclusters as a label-free fluorescent probe: Ferrous Ions and glucose   detection based on Fenton reaction and mechanistic investigation, Colloids   and Surfaces A: Physicochem. Eng. Aspects, 2021, 628: 127229.

[28] Zhiqing Zhang*, Jie Ma, Guodong Zhang,* Xiaoyan Ding, Ruyan Zhang,   Ting Zhou, Xiufeng Wang, Fang Wang. Large-scale DNA nanoarrays with   controllable fluorescence switch constructed by RCA simplified origami.   Langmuir, 2020, 36 (37): 10989-10995.

[29] Zhiqing Zhang*, Shanshan Wang, Jie Ma, Ting Zhou*, Fang Wang,   Xiufeng Wang, Guodong Zhang. Rolling Circle Amplification-Based Polyvalent   Molecular Beacon Probe Assisted Signal-Amplification Strategies for   Sensitive-Detection of B16 Cells. ACS Biomaterials Science & Engineering,   2020, 6(5): 3114-3121.

[30] Ting Zhou, Chenqi Zhang, Hong Wang, Xuefeng Kang, Zhiqing Zhang*,   Fang Wang, Xiufeng Wang, Guodong Zhang. Comparison Investigation on the   Adsorption Affinity of DNA Molecules to the Gold Surface Based on the Kinetic   and Thermodynamic Analysis of 4Nitrophenol Reduction, Journal of Physical   Chemistry C, 2020, 124: 4595-4604.

[31] Fang Wang, Zhiqing Zhang*, Ying Wei, Ting Zhou, Xiufeng Wang, Guodong   Zhang. Rheology study of wormlike micellar solution formed by   1-hexadecyl-3-methylimidazolium tetrafluoroborate ionic liquids in present of   sodium salicylate. Journal of Dispersion Science and Technology, 2020,   online.

[32] Zhiqing Zhang*, Shanshan Wang, Zichen Zhang, Jie Ma, Xiufeng Wang*,   Ting Zhou, Fang Wang, Guodong Zhang, Rolling Circle Amplification-based   Polyvalent Molecular Beacon Probe for Signal-amplifying and   Sensitive-Detection of Thrombin, Chemical Journal of Chinese Universities,   2019, 40(12): 2465-2470.

[33] Zhiqing Zhang, Tingting Liu, Shanshan Wang, Jie Ma, Ting Zhou, Fang   Wang, Xiufeng Wang, Guodong Zhang, DNA-Templated Gold Nanocluster as a Novel   Fluorometric Sensor for Glutathione Determination, Journal of Photochemistry   and Photobiology A: Chemistry, 2019, 370: 89-93.

[34] Zhiqing Zhang*, Tingting Liu, Changle Yue, Shanshan Wang, Jie Ma,   Ting Zhou*, Fang Wang, Xiufeng Wang, Guodong Zhang, Label-free and   Ultrasensitive Fluorescence Assay for Fe3+ Detection using DNA-Templated Ag   Nanoclusters, Colloids and Surfaces A: Physicochem. Eng. Aspects, 2019, 579:   123656.

[35] Ting Zhou, Jing Yuan, Zhiqing Zhang, Xia Xin, Guiying Xu*,  The comparison of imidazolium Gemini   surfactant [C14-4-C14im]Br2 and its corresponding monomer as corrosion inhibitors   for A3 carbon steel in hydrochloric acid solutions: Experimental and quantum   chemical studies, Colloids and Surfaces A: Physicochem. Eng. Aspects, 2019,   575: 57-65.

[36] 王芳, 张志庆, 李美蓉, 周亭, 王秀凤, 张国栋，原油降凝剂合成及性能测定的综合化学实验，化学教育（中英文），2020, 41 (16): 61-66。

[37] 张志庆，闫统江，工科院校建设新动能特色理科专业群的探索与实践，高等工程教育研究，2019，6，78-82。

[38] 周亭，陈俊峰，张志庆*，张国栋，王芳珠，短链醇溶液表面张力及表面吸附测定的实验研究，实验室研究与探索，2019,   38(1): 27-30。

[39] 周亭，刘淑贞，杨涛瑞，陈天银，张志庆*，金纳米颗粒的制备及性能研究在综合性实验教学中的应用，实验技术与管理，2019，36(4): 57-62。

[40] 周亭，杨世超，张志庆，咪唑啉表面活性剂的制备及吸附性能研究，实验室研究与探索，2019，38(5): 14-18。

[41] 王秀凤，魏浩杰，于传满，张志庆，周亭。光响应超分子凝胶的制备与性能，实验室研究与探索，2019，38(6): 27-29.

【2015-2018年】

[42] Zhiqing Zhang, Hongzhi Zhang, Fang Wang*, Guodong Zhang, Ting Zhou,   Xiufeng Wang, Shuzhen Liu, Tingting Liu, DNA Block Macromolecules Based on   Rolling Circle Amplification Act as Scaffolds to Build Large-scale Origami   Nanostructures, Macromolecular Rapid Communications, 2018, 39(15): 1800263.

[43] Zhiqing Zhang, Shuzhen Liu, Ting Zhou*, Hongzhi Zhang, Fang Wang,   Guodong Zhang, Xiufeng Wang, Tingting Liu, Salt-induced Assembly   Transformation of DNA-AuNPs Conju-gates Based on RCA Origami: From Linear   Arrays to Nanorings, Langmuir 2018, 34: 8904-8909.

[44] Chunhuan Shi, Zhiqing Zhang, Fang Wang, Yuxia Luan.   Active-targeting docetaxel-loaded mixed micelles for enhancing antitumor   efficacy, Journal of Molecular Liquids, 2018, 264: 172-178.

[45] Ting Zhou, Tingting Liu , Zhiqing Zhang,* Guodong Zhang, Fang Wang,   Xiufeng Wang, Shu zhen Liu, Hongzhi Zhang, Shanshan Wang, Jie Ma.   Investigation on catalytic properties of au nanorods with different aspect   ratios by kinetic and thermodynamic analysis, Journal of Solid State   Chemistry, 2018, 263: 11-17.  

[46] Zhiqing Zhang, Fang Wang, Huihui Nie, Ting Zhou, Guodong Zhang,   Xiufeng Wang, Mei Cui & Yunze Li. A simple strategy for the synthesis of   Zn-IL-SBA-15 by sol–gel and the application in desulfurization, Journal of Sol-Gel   Science and Technology, 2017, 82(3): 827-833.

[47] Zhiqing Zhang, Mei Cui, Fang Wang, Ting Zhou, Guodong Zhang &   Xiufeng Wang. Synthesis, characterization, and adsorptive desulfurization   behavior of Merrifield resin supported polymeric ionic liquids with different   alkyl chain lengths, Colloid Polym Sci, 2017, 295 (10): 1863–1871.

[48] Ting Zhou, Zhiqing Zhang*, Xuemei Zhang, Chen Wang, Guiying Xu and   Yanlian Yang. Self-assembled Chiral Nanostructures of Amphiphilic Peptide:   From Single Molecule to Aggregate, Journal of Peptide Science, 2017, 23:   803-809.

[49] Shuzhen Liu, Zhiqing Zhang*, Fang Wang, Ting Zhou, Xiufeng Wang,   Guodong Zhang, Tingting Liu, Hongzhi Zhang, Study on the Synthesis of DNA via   Rolling Circle Amplification, Acta Physico-Chimica Sinica, 2017, 33(10):   2052-2057.

[50] Hongzhi Zhang, Zhiqing Zhang*, Fang Wang, Ting Zhou, Xiufeng Wang,   Guodong Zhang, Tingting Liu, Shuzhen Liu, Application of Structural DNA   Nanotechnology, Acta Physico-Chimica Sinica, 2017,33(8):1520-1532.  

[51] Chunhuan Shi, Zhiqing Zhang, Fang Wang, Xiaoqing Ji, Zhongxi Zhao,   Yuxia Luan. Docetaxel-loaded PEO–PPO–PCL/TPGS mixed micelles   for overcoming multidrug resistance and enhancing antitumor efficacy. Journal   of Materials Chemistry B, J. Mater. Chem. B, 2015, 3(20), 4259-4271.

[52] Chunhuan Shi, Zhiqing Zhang, Jiaxing Shi, Fang Wang, Yuxia Luan.   Co-delivery of docetaxel and chloroquine via PEO–PPO–PCL/TPGS micelles for overcoming multidrug   resistance.International Journal of Pharmaceutics, 2015, 495(2): 932–939.

[53] Fang Wang, Zhiqing Zhang*, Tao Wang, Yunze Li, Mei Cui. Synthesis,   Characterization, and Demulsification Behavior of Amphiphilic Dendritic Block   Copolymers, Journal of Dispersion Science and Technology, 2015, 36(8):   1097-1105.

[54] 赫庆坤，张洪芝，朱文璇，王秀凤，周亭，张志庆*，基于超分支滚环扩增技术的DNA水凝胶的制备及性能研究，胶体与聚合物，2018，36（3）：137-139.

[55] 张志庆，刘臻，王芳，孙鹏燕，周亭。工科院校构建理科创新平台探究，实验室研究与探索，2018，37(4)，258-261.

[56] 张志庆，王芳，杨春天，姜显宏。疏水缔合两亲高分子的合成与表面活性，实验室研究与探索，2018, 37(5)，35-38.

[57] 周亭，王芳珠，张志庆*，张国栋，王秀凤，张予辉，王长崴，工科非化学类专业物理化学的教学设计与实践，大学化学，2018, 33(12): 1-7.

[58] 周亭，杨世超，张志庆*，张国栋，王芳珠，张予辉，王芳，王秀凤，芘荧光探针法测定表面活性剂聚集体参数实验研究，实验技术与管理，2018,35 (1): 53-56。

[59] 王秀凤，张志庆，王芳珠，张国栋，周亭，基于云课堂的物理化学教学改革与探索，高等理科教育，2018，3：79-83.

[60] 王秀凤，王芳珠，张志庆，以应用为导向的《胶体与界面化学》互动式教学改革与实践，高教论坛，2018, 10: 24-26.

[61] 王秀凤，张国栋，张志庆，王芳，周亭，二肽衍生物水凝胶的染料吸附性能综合化学实验，实验技术与管理，2018, 35(8): 206-210.

[62] 张志庆，王芳，周亭，王秀凤，张国栋，薛庆忠，刘臻。研究生优质课《胶体与界面化学》的改革与探索，化学教育，2017，38(24): 58-61.

[63] 王芳，吕仁庆，于剑锋，张志庆. 关于卤化硼的Lewis酸性强度的讨论，大学化学，2016, 31 (12), 79-82.

[64] 张志庆，王芳，周亭，王秀凤，张国栋，梁茜茜，李昀泽。Gemini 表面活性剂黏弹性流体的流变性研究，胶体与聚合物，2016,34（4）：147-150.

【2014年之前】

[65] Zhiqing Zhang, M. Monsur Ali, Mark A. Eckert, Dong-ku Kang, Yih   Yang Chen, Leonard S. Sender, David A. Fruman, Weian Zhao. A polyvalent   aptamer system for targeted drug delivery, Biomaterials, 2013, 34(37),   9728-9735.

[66] M. Monsur Ali, Feng Li, Zhiqing Zhang, Kaixiang Zhang, Dong-ku   Kang, J. Ankrum, C. Le, Weian Zhao. Rolling circle amplification: A versatile   tool for chemical biology, materials science and medicine, Chem. Soc. Rev.,   2014, 43(10), 3324-3341.

[67] Zhiqing Zhang, Mark A. Eckert, M. Monsur Ali, Linan Liu, Dong-ku   Kang, Elizabeth Chang, Leonard S. Sender, David A. Fruman, Weian Zhao.   DNA-Scaffolded Multivalent Ligands to Modulate Cell Function, Chembiochem,   2014, 15(9): 1268-1273.

[68] Chengcheng Ren, Fang Wang*, Zhiqing Zhang, Huihui Nie, Nan Li, Mei   Cui. Synthesis, surface activity and aggregation behavior of   Geminiimidazolium surfactants 1,3-bis(3-alkylimidazolium-1-yl)   propanebromide, Colloids and Surfaces A: Physicochem. Eng. Aspects, 2015,   467: 1-8.

[69]Shan Yang, Zhiqing Zhang*, Fang Wang, Lijuan Feng, Xiaoxia Jiang,   Chuntian Yang, Xianhong Jiang, and Guoqiang Liu. The synthesis and the bulk   rheological properties of the highly-branched block polyethers, Polymer   Science Series A, 2014, 56(6), 917-927.

[70] Lijuan Feng, Zhiqing Zhang*, Fang Wang, Tao Wang, Shan Yang.   Synthesis and Evaluation of Alkyl Acrylate-Vinyl Acetat-Maleic Anhydride   Terpolymers as Cold Flow Improvers for Diesel Fuel, Fuel Processing   Technology, 2014, 118, 42-48.

[71] Lanxia Zhao, Jing Liu, Longlong Zhang, Ya Gao, Zhiqing Zhang, Yuxia   Luan. Self-assembly properties, aggregation behavior and prospective   application for sustained drug delivery of a drug-participating catanionic   system, International Journal of Pharmaceutics, 2013, 452(1-2), 108-115.

[72] Yan Lin, Fang Wang, Zhiqing Zhang, Jie Yang, Ying Wei.   Polymer-supported ionic liquids: synthesis, characterization and application   in fuel desulfurization, Fuel, 2014, 116, 273-280.  2014-1-1

[73] Ying Wei, Fang Wang, Zhiqing Zhang, Chengcheng Ren, Yan Lin.   Micellization and Thermodynamic Study of 1-Alkyl-3-methylimidazolium   Tetrafluoroborate Ionic Liquids in Aqueous Solution, J. Chem. Eng. Data,   2014, 59 (4), 1120–1129.

[74] Nan Li, Fang Wang,* Zhiqing Zhang, Huihui Nie, Chengcheng Ren, and   Mei Cui. Synthesis and Desulfurization Performance of Functional Silica Gel   Modified by Polymeric 1‑Vinyl-3-ethylimidazolium Tetrafluoroborate Ionic Liquids, Ind.   Eng. Chem. Res. 2014, 53(43), 16664−16671.

[75] Lifang Xu, Zhiqing Zhang*, Fang Wang, Dongdong Xie, Shan Yang, Tao   Wang, Lijuan Feng, Chengchai Chu. Synthesis, characterization, and   self-assembly of linear poly(ethylene oxide)-block–poly(propylene   oxide)-block–poly(e-caprolactone) (PEO–PPO–PCL) copolymers. J. Colloid and   Interface Sci. Journal of Colloid and Interface Science2013, 393, 174-181.

[76] Fang Wang, Zhiqing Zhang*, Jie Yang, Liping Wang, Yan Lin, Ying   Wei. Immobilization of room temperature ionic liquid (RTIL) on silica gel for   adsorption removal of thiophenic sulfur compounds from fuel. Fuel, 2013, 107,   394–399.

[77] Shan Yang, Zhiqing Zhang*, Fang Wang, Lijuan Feng, Tao Wang.   Surface Properties and Aggregation Behaviors of Amphiphilic Hyperbranched   Block Polyethers in Aqueous Solution, Journal of Polymer Research, 2013,   20(8), 205.

[78] Shan Yang, Zhiqing Zhang*, Fang Wang, Xiaoxia Jiang, Chunming Liu,   Xixi Liang. Cosolvent Effect on the Aggregation of Amphipathic   Highly-Branched Diblock Polyether in Aqueous Solution, Journal of Polymer   Research, 2013, 20, 307.

[79] Zhiqing Zhang, F. Wang, D. Li, J. Yang. Interfacial Composition,   Thermodynamic Properties and Structural parameters of   [bmim][BF4]+Cetyltrimethylammonium Bromide+Alkanol+Toluene Microemulsion,   Journal of Dispersion Science and Technology, 2012, 33, 141-146.

[80] Fang Wang, Zhiqing Zhang*, Dong Li, Jie Yang, Chengchai Chu, Lifang   Xu. Dilution Method Study on the Interfacial Composition, Thermodynamic   Properties and Structural Parameters of [bmim][BF4]+Brij-35+1-butanol+Toluene   Microemulsion,J. Chem. Eng. Data, 2011, 56 (8):  3328–3335.

[81] Zhiqing Zhang, Fang Wang. Aggregation behavior of polyether block   copolymers with dendritic structure in aqueous solutions. Journal of   Dispersion Science and Technology 2008, 29, 1092-1097.

[82] Zhiqing Zhang, Jin Mu. Hydrothermal synthesis of ZnO nano-bundles   controlled by PEO-PPO-PEO block copolymers. J. Colloid and Interface Sci.   2007, 307, 79-82.

[83] Zhiqing Zhang, Jin Mu. Hydrothermal synthesis of γ-MnOOH nanowires and α-MnO2 dendritic clusters in different oxidation systems. Solid   State Communications 2007, 141, 427-430.

[84] Zhiqing Zhang, Jin Mu. Effect of hydrothermal time, pH and alkali   on crystal phase and morphology of manganese oxides. Journal of Dispersion   Science and Technology 2007, 28(5), 793-796.

[85] Zhiqing Zhang, Jin Mu. Fabrication of ZnO nanorods in colloidal   systems formed by PEO‐PPO‐PEO block copolymers. Journal of   Dispersion Science and Technology 2006, 27, 769-772.

[86] Zhiqing Zhang, Guiying Xu, Fang Wang, Shuli Dong, Yijian Chen. The   demulsification by amphiphilic dendrimer copolymers. J. Colloid and Interface   Sci., 2005, 282, 1-4.

[87] Zhiqing Zhang, Guiying Xu, Fang Wang, and Guangqing Du. Aggregation   behaviors and interfacial properties of oxyethylated nonionic surfactants.   Journal of Dispersion Science and Technology 2005, 26(3), 297-302.

[88] Zhiqing Zhang, Guiying Xu, Fang Wang, Shuli Dong, Yimin Li.   Characterization and Demulsification of Poly(ethylene oxide)-block-Poly   (propylene oxide)- block-Poly(ethylene oxide) Copolymers. J. Colloid and Interface   Sci. 2004, 277, 464-470.

[89] Xia Xin, Guiying Xu, Yajing Wang, Hongzhi Mao, Zhiqing Zhang.   Interaction between star-like block copolymer and sodium oleate in aqueous   solutions. European Polymer Journal, 2008, 44, 3246-3255.

[90] Xia Xin, Guiying Xu, Taotao Zhao, Yanyan Zhu, Xiaofeng Shi, Houjian   Gong, Zhiqing Zhang. Dispersing Carbon Nanotubes in Aquous Solutions by a   Starlike Block Copolymer. Journal of Physical Chemistry C, 2008, 112,   16377-16384.

[91] Jin Mu, Zhenfang Gu, Lei Wang, Zhiqing Zhang, Hua Sun, Shi-Zhao   Kang. Phase and shape controlling of MnS nanocrystals in the solvothermal   process. Journal of Nanoparticle Research 2008, 10, 197-201.

[92] Fang Wang, Bo Fang, Zhiqing Zhang, Saiyu Zhang, Yandong Chen. The   effect of alkanol chain on the interfacial composition and thermodynamic   properties of diesel oil microemulsion. Fuel, 2008, 87(12), 2517.

[93] Fang Wang, Bo Fang, Zhiqing Zhang, Saiyu Zhang. Mechanism of   electrical percolation of w/o microemulsions formed by nonionic surfactants.   Journal of Dispersion Science and Technology, 2008, 29(8), 1166-1172.

[94] Fang Wang, Bo Fang, Zhiqing Zhang, Lijie Qiao, Yandong Chen.   Dilution method study on the interfacial composition, thermodynamic   properties and structural parameters of HCl /cetyltrimethylammonium chlorine   /alkanol/ diesel oil microemulsion: Effect of HCl in water pool. Journal of   Chemical and Engineering data, 2008, 53(6), 1256-1261.

[95] Xia Xin, Guiying Xu, Zhiqing Zhang, Yijian Chen and Fang Wang.   Aggregation behavior of star-like PEO–PPO–PEO block copolymer in aqueous solution. European Polymer Journal,   2007, 43(7), 3106-3111.

[96] Lingyun Liu, Zhiqing Zhang, Shi-Zhao Kang and Jin Mu. Effect of   SnO2 nanocrystals on the emission of Eu3+ ions in silica matrix. Journal of   Dispersion Science and Technology 2007, 28(5), 769-772.

[97] Fang Wang, Guiying Xu, Zhiqing Zhang, Xia Xin. Synthesis of   monodisperse CdS nano-spheres in inverse microemulsion system formed by   dendritic polyether copolymer. Eur. J. Inorg. Chem. 2006, 1, 109.

[98] Fang Wang, Guiying Xu, Zhiqing Zhang, Shue Song, Shuli Dong. A   systematic morphosynthesis of barium sulfate in the presence of phosphonate   inhibitor. J. Colloid and Interface Sci. 2006, 293, 394.

[99] Jin Mu, Zhenfang Gu, Zhiqing Zhang, Xiangqing Li, Shi-Zhao Kang,   Lei Wang. Effect of hydrothermal on the crystalline phase and morphology of   manganese oxide nanocrystals. Journal of Dispersion Science and Technology   2006, 27, 1223.

[100] Zhenfang Gu, Hua Sun, Jin Mu, Zhiqing Zhang, Lei Wang, Shi-Zhao   Kang. Hydrothermal synthesis and characterization of Cd1-xMnxS (0≤x<1) nanocrystals.   Journal of Dispersion Science and Technology 2006, 27, 1187.

[101] Fang Wang, Guiying Xu, Zhiqing Zhang. The effect of pH on   morphological control of barium hydrogen phosphate crystal by a   double-hydrophilic copolymer. Materials Letter2005,59(7) , 808.

[102] Fang Wang, Guiying Xu, Zhiqing Zhang. Morphology control of barium   sulfate by PEO-PPO-PEO as crystal growth modifier. Colloids and Surfaces A   2005,259, 165.

[103] Gui-Ying Xu, Ai-Min Chen, Zhi-Qing Zhang, Shu-Li Dong, Li-Qiang   Zheng, Ye-Bang Tan. Aggregation behaviors of amphiphilic copolymers with   methylacrylic acid segments at interface. Colloids and surfaces A 2005,   257-258, 503.

[104] Xiaorong Cao, Guiying Xu, Yinming Li, Zhiqing Zhang. Aggregation   of poly(ethylene oxide)-poly(propylene oxide) block copolymers in aqueous   solution: DPD simulation study. J. Phys. Chem. A 2005, 109, 10418.

[105] Yiming Li, Guiying Xu, Yuxia Luan, Shiling Yuan, Zhiqing Zhang.   Studies on the interaction between tetradecyl dimethyl betaine and sodium   carboxymethyl cellulose by DPD simulations. Colloids and Surfaces A 2005,   257-258, 385.

[106] Qiang Shen, Hao Wei, Liancheng Wang, Yong Zhou, Ying Zhao, Zhiqing   Zhang, Dujin Wang, Guiying Xu, Duanfu Xu. Crystallization and aggregation   behaviors of calcium carbonate in the presence of poly(vinylpyrrolidone) and   sodium dodecyl sulfate. Journal of Physical Chemistry B, 2005, 109(39),   18342-18347.

[107] Li Xiao, Guiying Xu, Zhiqing Zhang, Youbao Wang, Ganzuo Li.   Adsorption of Sodium Oleate at the Interface of Oil Sand/Aqueous Solution.   Colloids and surfaces A2003, 224, 199-206.

[108] Yuxia Luan, Guiying Xu, Shiling Yuan, Li Xiao, Zhiqing Zhang.   Comparative Studies of Structurally Similar Surfactants: Sodium Bis   (2-ethylhexyl) Phosphate and Sodium Bis (2-ethylhexyl) Sulfosuccinate.   Langmuir 2002, 18, 8700.

[109] Yuxia Luan, Guiying Xu, Shiling Yuan, Li Xiao, Zhiqing Zhang.   Investigations on NaDEHP and AOT: Computer Simulation and Surface Tension   Measurements.  Colloids and surfaces A   2002, 210, 61.

[110]   张志庆，王涛，王芳，杨姗，蒋晓霞，李昀泽. 破乳剂的RSN 值与破乳脱水性能的关系，胶体与聚合物，2014，32(4)，147-149. 

[111]   张志庆，王芳，蒋晓霞，梁茜茜，刘春鸣. 环境响应性两亲嵌段共聚物的自组装及其药物控释研究进展，胶体与聚合物，2014，32(1)，44-48.  2014.3.1

[112]   张志庆，王芳，任超. 电导法与最大压差法测表面活性剂CMC的实验比较，实验技术与管理，2013，30(1)，41-45.

[113]   张志庆，王芳. 新型稠油破乳剂分子结构对孤东稠油脱水的影响，油田化学，2006，23(4)，325-328.

[114]   张志庆，徐桂英，王芳，谭业邦，陈贻建. 新型酚胺聚醚破乳剂的原油脱水研究，山东大学学报，2004，39(3)，84.

[115]   张志庆，徐桂英，肖莉，栾玉霞，张秀君，张国荣，刘高友. 十二烷基甜菜碱/十二烷基硫酸钠复合体系与原油间的界面张力，山东大学学报，2002, 37(2), 153.

[116]   张志庆，徐桂英，叶繁，郑立强，栾玉霞. 十二烷基甜菜碱/十二烷基硫酸钠复合体系的表面活性，物理化学学报，2001，17(12)，1122.

[117]   张志庆，徐桂英，吴涛，刘春博，胡清萍，刘军. 矿化水对稠油乳化降粘剂SDGD降粘效果的影响，油田化学，2001，18(4)，302.

2.专利

[1] 2024.02，张志庆，马鸣宇，王灏然，槐子宇，王芳。发明专利“一种用于天然气水合物清洁压裂液的阴-非两性双子表面活性剂及其制备方法”，授权专利号：ZL 202210602245.6。

[2] 2023.09，张志庆，刘娜娜，杨春天，王芳，张国栋，周亭，王秀凤。发明专利“一种分子信标、其构建方法及应用”，授权专利号ZL 202010694129.2。

[3] 2023.08，张志庆，马帅，周子坤，杨春天，王芳。发明专利“一种多价聚阴离子含油污水净水剂及制备方法”，授权专利号：ZL 202111541119.6。

[4] 2023.07，张志庆，王师修，张桂珍，王芳，杨春天。发明专利“一种用于天然气水合物清洁压裂液的表面活性剂及其制备方法”，授权专利号：ZL 202111475013.0，

[5] 2022.06，张志庆，张子辰，杨春天，王芳，张国栋，王秀凤，周亭。发明专利“一种多价适配体DNA纳米梯子及其制备方法和应用”，授权专利号：ZL 202010856470.3。

[6] 2019.04，张志庆，王芳，杨春天，周亭，王秀凤，张国栋。发明专利“原油破乳剂及其制备方法”，授权专利号ZL 201710041384.5。

[7] 2019.08，张志庆，王芳，杨春天，周亭，王秀凤，张国栋。发明专利“原油降凝剂及其制备方法”，授权专利号ZL 201710052068.8。

[8] 2012，张志庆，靳路超，王芳。发明专利“一种高效浓缩型阿维菌素-高效氯氰菊酯水乳剂及其制备方法”，授权专利号：ZL 201010134853.6。

[9] 2007，徐桂英，张志庆，王芳。发明专利“含水含蜡原油低温快速破乳剂及其制备方法”，授权专利号ZL 200310105425。

[10] 2013，美国专利“MULTIVALENT DRUGS FOR THE   TREATMENT OF INFLAMMATION AND CANCER AND METHODS FOR MAKING AND USING THEM”, Application Serial No. (USSN) 61/868,486.

[11] 2021.12，张志庆，徐东彦等。一种DNA纳米载体复合物及其制备方法和应用，专利号：202111598473.2。

[12] 2023.03，张志庆，张毓琨等。一种用于天然气水合物压裂液的两亲共聚物，其制备方法及用途，专利号：202211357303.X。

[13] 2024.01，张志庆，张雨等。一种破乳清水一体化的超分子聚醚及其制备方法，专利号：202410024822.7。

[14] 2024.06，张志庆，王汐璆等。一种用于天然气水合物清洁压裂液的噻唑烷酮基两性Gemini表面活性剂及其制备方法，专利号：202410707336.5。

[15] 2024.11，张志庆，杜欢等。一种多功能纳米复合物及其制备方法和应用，专利号：202411562876.5。

◎代表性著作

[1] 2019.2，主编石油高等教育“十三五”规划教材，《胶体与界面科学》，中国石油大学出版社。

[2] 2017.7，主编《中国化学会第十六届胶体与界面化学会议论文集》，中国石油大学出版社。

[3] 2011.10，主编国家级网络精品课教材，《物理化学》，化工出版社。

◎获奖情况及荣誉称号

[1] 2021年12月，“原油破乳剂及其制备方法”获得中国石油和化学工业联合会专利优秀奖；

[2] 2020年7月，“结构DNA纳米技术应用新进展”获评为《物理化学学报》高被引论文奖；

[3] 2019年12月，“搭建理科创新平台，培养本科创新人才”荣获“中国石油大学（华东）教学成果奖二等奖”；   

[4] 2019年9月，荣获“中国石油大学学生就业工作优秀教师”称号；

[5] 2019年5月，荣获中国石油大学青年五四奖章；

[6] 2017年，打造优质课程资源，改革教育教学方法，培养化学专业创新人才，校级优秀教学成果奖二等奖；

[7] 2017年，《胶体与界面化学》获得山东省研究生优质课；

[8] 2017.9.4，山东省高等学校创新创业教育导师；

[9] 2016.12.18，获得中国石油大学“校企合作先进个人”称号；

[10] 2015，“理念引领，高端定位，加强对化学学科低年级学生实践创新能力的培养”，校级优秀教学成果奖二等奖；

[11] 2015，物理化学虚拟仿真实验室建设，山东省教育技术与装备协会，年度优秀论文二等奖；

[12] 2014.12年，“两亲性高度支化嵌段聚醚的合成及自组装研究”荣获校级优秀硕士学位论文指导教师；

[13] 2015.01，“两亲嵌段共聚物的胶束自组装及其载体应用”获得黄岛区自然科学奖二等奖；

[14] 2014.11.28，获得中国石油大学“石大科创教学之星”奖教金；

[15] 2014.7.30，“研究型化学实验教学体系的构建与实践”，第七届山东省高等教育教学成果三等奖；

[16] 2013年，中国石油大学大学生科技指导优秀教师称号；

[17] 2012年，“研究型化学实验教学体系的构建与实践”校级优秀教学成果一等奖；

[18] 2012年，“电导法与最大压差法测表面活性剂CMC的实验比较” 获得山东省教育技术与装备协会组织的2011年度优秀论文三等奖；

[19] 2012年，“挑战杯”竞赛优秀指导教师；

[20] 2010年，青岛市经济技术开发区优秀青年人才；

[21] 2010年，挑战杯山东省级优秀指导教师；

[22] 2010年，挑战杯创业大赛国家银奖指导教师；

[23] 2010年，中国石油大学大学生科技指导优秀教师称号；

[24] 2009年，中国石油大学首届人才建设工程骨干教师；

[25] 2009年，山东省物理化学委员会委员；

[26] 2008年，克拉玛依石化奖教金；

[27] 2007年，“三元复合驱油水分离技术的研究与应用”获东营市科技成果三等奖；

[28] 2005年，全国东方杯胶化之星三等奖；

[29] 2004年，“低温快速原油破乳剂”成果鉴定为国际先进水平；

[30] 2004年，挑战杯山东省一等奖。

◎执教课程

本科生：《胶体与界面化学》《物理化学》《物理化学实验》

研究生：《胶体与界面化学》

◎招收及指导研究生情况

1.指导学生情况

指导博士、硕士研究生40余名，指导大学生创新创业项目18项，指导挑战杯及创业大赛6项（其中一项获国家级银奖），先后担任30余名本科生的学业导师。

2.招生专业及要求

   有化学、化工、应用化学、材料化学、生物化学、高分子化学等化学化工类专业背景的学生，均可报考本课题组的博士、硕士研究生。

◎学术兼职

[1] 山东省化学化工学会理事；

[2] 《胶体与聚合物》期刊编委；

[3] 教育部学位中心学位论文评审专家；

[4] 教育部评估中心评估专家;

[5] 学术桥评审评估专家；

[6] 山东省物理化学委员会委员；

[7] 中国化学会会员；

[8] 中国抗癌协会纳米肿瘤学专业委员会会员；

[9] ACS Nano, Biomaterials, Advanced   Science, Soft Matter, Analytical Chemistry, Macromolecules,   Biomacromolecules, Chemical Engineering Journal, Fuel, Journal of Molecular   Liquids等国际top期刊审稿人，常年担任Journal of Colloid and   Interface Science期刊特邀审稿人。